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Writer's pictureKiki Maree

UTIs, Skenitis, and Other Commonly Misdiagnosed Conditions: Symptoms, Prevention, and Treatment

Urinary tract infections (UTIs) are a well-known and common issue, particularly for people with vulvas. However, other conditions, such as skenitis and interstitial cystitis, can mimic the symptoms of UTIs, leading to frequent misdiagnoses and ineffective treatments. Understanding the causes, symptoms, and prevention strategies for UTIs, as well as recognizing similar conditions, is crucial for maintaining sexual and urinary health.


In this article, we will explore why people with vulvas experience more UTIs, how to prevent them, the role of Skene’s glands and skenitis, conditions that can be misdiagnosed as UTIs, and potential supplements that may help prevent infections.


Why Are UTIs More Common in Female Bodies?

UTIs are more prevalent in people with vulvas due to anatomical differences. The urethra, which carries urine from the bladder out of the body, is shorter in those with vulvas compared to people with penises. This shorter distance allows bacteria, especially E. coli, to travel more easily into the bladder and cause infection. Additionally, the urethra’s proximity to the anus increases the risk of bacterial transfer, especially during sexual activity.


In contrast, people with penises have a longer urethra, providing a greater barrier for bacteria to travel before reaching the bladder, which lowers the chances of infection.


Skenitis: The Overlooked Condition

Skenitis refers to the infection or inflammation of the Skene’s glands, small glands located near the urethral opening in people with vulvas. These glands secrete fluid to lubricate the urethral area, particularly during sexual arousal. Inflammation of these glands can cause symptoms similar to a UTI, including:


  • Burning during urination

  • Painful urination

  • Pelvic discomfort or pressure

  • Swelling or tenderness near the urethra

  • Pain during sexual activity


Due to its similar symptoms, skenitis is often misdiagnosed as a UTI or cystitis. Unlike UTIs, which affect the bladder or urinary tract, skenitis specifically involves the Skene’s glands. If untreated or misdiagnosed, the condition can persist despite typical UTI treatments.


Conditions Commonly Misdiagnosed as UTIs or Cystitis

Aside from skenitis, several other conditions can be mistaken for UTIs due to overlapping symptoms. These include:


1. Interstitial Cystitis (IC)

Interstitial cystitis, or painful bladder syndrome, is a chronic condition that causes bladder pain and discomfort without the presence of bacteria. Symptoms include frequent urination, pelvic pain, and pressure, often mistaken for a UTI. However, antibiotics will not alleviate IC, as it is not caused by bacteria .


2. Vaginitis

Vaginitis, which includes infections like bacterial vaginosis or yeast infections, can cause burning and irritation similar to UTI symptoms. However, vaginitis is usually accompanied by discharge and itching, distinguishing it from a urinary infection .


3. Sexually Transmitted Infections (STIs)

Certain STIs, such as chlamydia and gonorrhea, can cause symptoms similar to a UTI, including burning during urination and pelvic pain. If UTI treatment does not resolve symptoms, STI testing should be considered .


4. Urethral Syndrome

Urethral syndrome involves inflammation of the urethra, leading to similar symptoms as a UTI but without bacterial infection. Causes may include trauma, irritants, or sexual activity.


5. Kidney Stones

Kidney stones can cause sharp lower back or abdominal pain and blood in the urine, symptoms that can sometimes mimic a UTI. However, the severe, radiating pain is more characteristic of kidney stones than a typical UTI .


Preventing UTIs: Practical Strategies

Several practical steps can help prevent UTIs and other urinary-related conditions:


1. Urinating After Penetrative Sex

Urinating after sex is one of the most effective ways to flush out bacteria that may have entered the urethra during sexual activity. This reduces the risk of infection by preventing bacteria from traveling to the bladder.


2. Engorgement and Penetration

Proper genital engorgement (swelling of tissues during arousal) before penetration is vital. Engorgement naturally closes the urethral opening, which helps prevent bacteria from entering the urinary tract. Penetration before full arousal can increase the risk of infection due to increased exposure of the urethral opening.


3. Hydration

Staying hydrated helps flush bacteria from the urinary tract. Drinking plenty of water and urinating regularly also supports urinary health.


4. Wiping from Front to Back

For people with vulvas, wiping from front to back after using the toilet helps prevent bacteria from being transferred from the anus to the urethra.


5. Choosing Breathable Underwear

Wearing cotton underwear and avoiding tight clothing can reduce moisture and bacteria growth in the genital area, promoting better urinary health.


Supplements for UTI Prevention

Several supplements have been shown to help prevent UTIs or support urinary health:


1. D-mannose

D-mannose is a sugar found in fruits like cranberries and can prevent E. coli from adhering to the walls of the urinary tract. Some studies suggest it may be as effective as antibiotics for preventing recurrent UTIs in some people .


2. Non-Acidic Vitamin C

Vitamin C is known for boosting immune function, and non-acidic forms of the vitamin can help acidify urine without irritating the bladder. Some evidence suggests this creates an environment that is less conducive to bacterial growth .


3. Goldenseal

Goldenseal, a traditional herbal remedy, contains berberine, an antimicrobial compound. While its effectiveness in preventing UTIs is not fully confirmed by research, some evidence suggests it may have potential for urinary health support .


4. Cranberry Extract

While cranberry juice is often touted as a UTI remedy, cranberry extract supplements are more effective at preventing bacteria from adhering to the urinary tract lining. It’s important to choose sugar-free options to avoid the negative effects of added sugars in juices .


Skenitis vs. UTIs: Key Differences

While both skenitis and UTIs cause similar symptoms, there are key differences:


Location of infection: UTIs involve the bladder or urinary tract, while skenitis affects the Skene’s glands.


Symptom focus: Skenitis may involve more localized tenderness or swelling near the urethra, while UTIs generally cause more diffuse pelvic or bladder discomfort.

Treatment response: Skenitis may not respond to typical UTI treatments if the underlying issue is not addressed.


When to See a Healthcare Provider

If UTI symptoms persist after treatment or recur frequently, it is essential to consult a healthcare provider. Persistent or recurring symptoms may indicate a misdiagnosis or a condition like skenitis or interstitial cystitis. Misdiagnosed conditions can lead to chronic pain or complications if left untreated. Additionally, while supplements can support urinary health, they should not replace professional medical care, especially in cases of infection.

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